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Our mission is to provide healthcare professionals with unbiased clinical research information, easily.

Currently, you can access the following clinical trials being conducted worldwide:

370533 studies
in
219 countries
Clinical trial information and results are updated daily from ClinicalTrials.gov. The latest data update was conducted on 04/16/2021.
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Drug Interventions

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Clinical trial information and results are updated daily from ClinicalTrials.gov. The latest data update was conducted on 04/16/2021.
Displaying: 10,179 trials in your specialties ()
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Developing an Instrument for Measuring Walking Ability in Patients With Spinal Stenosis

  • Status
    Active, not recruiting
  • Phase
    N/A
  • Condition
    Lumbar Spinal Stenosis
View Full Trial
INTERVENTION

Other: Standard Movement Protocol, Device: Accerelerometer Monitoring

Eligibility
  • Ages:
  • Sexes: All
  • Accepts Healthy Volunteers:
Locations

Spine Centre of Southern Denmark, Middelfart, Denmark

Brief Summary

Background: People would like to live longer while still staying healthy, active and able to enjoy life. Unfortunately, many elderlies get symptoms that prevent them from this. A disease with such symptoms is Lumbar Spinal Stenosis (LSS), which comes with severe pain and reduction of walking ability. One of the main goals when treating patients with spinal stenosis, is to increase their walking ability in everyday life. As of today, there is no adequate measurement instrument for the task. Many have encountered step counters in mobile phones or as wristbands. Unfortunately, they are not validated and tested in playing the part of a scientific instrument when measuring walking in patients with spinal stenosis. This research project will develop the step counter- e.g. accelerometer, to be an accurate and feasible measurement of walking activity in daily living. The measure is expected to be sensitive enough for therapy evaluation. This will enable researchers to make relevant and informed interventions on increasing walking ability. Furthermore, the measure is expected to grant further research into its diagnostic possibilities and prognostic uses, where it could become a valuable clinical tool. By developing the accelerometer measure, health care and health policies can be guided towards effectively helping spinal stenosis patients to an active everyday life. The aim of the study is to develop a valid and feasible measure of walking ability in patients with lumbar spinal stenosis. Methods: The study will be performed in three phases. In the first phase, the accelerometer measurement method will be developed and tested in a standardized environment. In the second phase, patients with lumbar spinal stenosis and healthy participants will be instructed to wear an accelerometer for seven days during their normal everyday life. Furthermore, they will be asked to perform a walking test and fill out questionnaires. In the third phase, previously included patients which have received decompressive surgery to relieve symptoms of LSS, will be invited to come to the clinic for a follow-up three months after surgery. The follow-up will repeat the accelerometer measures, walking test and questionnaires performed in the second phase.

Cost- Effectiveness of a Face-to-Face Rehabilitation Program vs an Telemedicine Program in Chronic Low Back Pain

  • Status
    Active, not recruiting
  • Phase
    N/A
  • Condition
    Low Back Pain
View Full Trial
INTERVENTION

Other: Face-to-Face Rehabilitation program, Other: Telemedicine program

Eligibility
  • Ages:
  • Sexes: All
  • Accepts Healthy Volunteers:
Locations

Universidad de Almería, Almería, Andalucía, Spain

Brief Summary

Perform a cost-utility analysis in patients with chronic low back pain through electroanalgesia treatment and exercises administered by telemedicine program versus face-to-face program

Cognitive-driven ADL Impairment as a Predictor for PDD

  • Status
    Active, not recruiting
  • Phase
    N/A
  • Condition
    Parkinson Disease
View Full Trial
INTERVENTION

Diagnostic Test: Functional Activities Questionnaire

Eligibility
  • Ages:
  • Sexes: All
  • Accepts Healthy Volunteers:
Locations

University hospital of Tuebingen, Tuebingen, Baden-Württemberg, Germany

Brief Summary

Mild cognitive impairment in Parkinson's disease (PD-MCI) is the highest risk factor for Parkinson's disease dementia (PDD). The core feature for differentiating PDD from PD-MCI is the loss of the ability to perform activities of daily living (ADL). As Parkinson's Disease (PD) is primarily a movement disorder, the distinction between motor and cognitive contributions to ADL in PD is an obvious challenge, which the investigators aimed to explore in this study. The goal of the study is to evaluate whether PD-MCI patients with more pronounced, cognitive-driven ADL impairment are at higher risk for cognitive worsening and PDD. A longitudinal follow-up assessment of 262 non-demented PD patients will be conducted over the next two years, with a comprehensive clinical assessment as well as biomarker sampling (cerebrospinal fluid and blood markers). Primary longitudinal outcome will be conversion to PDD and PD-MCI. Conversion rates of patients with and without additional mild cognitive-driven ADL impairment at baseline will be compared. Novel scores of the Pfeffer Functional Activities Questionnaire (FAQ) are used to assess instrumental ADL, differentiating between cognitive- and motor-driven ADL impairment in PD-MCI.

Effectiveness of a Home Rehabilitation Program vs an e-Health Program in Patients With Chronic Low Back Pain

  • Status
    Active, not recruiting
  • Phase
    N/A
  • Condition
    Low Back Pain
View Full Trial
INTERVENTION

Other: Home Rehabilitation Program, Other: e-Health program

Eligibility
  • Ages:
  • Sexes: All
  • Accepts Healthy Volunteers:
Locations

University of Almería, Almería, Andalucía, Spain

Brief Summary

The main objetive of this study is to analyze the effectiveness of a home rehabilitaton program vs a e-Health program. Therapeutic approach will be by electroanalgesia and exercise of patients with chronic low back pain.

Health in the Right Measure: Promoting Healthy Food and Regular Physical Activity Practice for UFRJ Servers

  • Status
    Active, not recruiting
  • Phase
    N/A
  • Condition
    Human
View Full Trial
INTERVENTION

Behavioral: Health in the right measure

Eligibility
  • Ages:
  • Sexes: All
  • Accepts Healthy Volunteers:
Locations

Vanessa Chaia Kaippert, Rio de Janeiro, Brazil

Brief Summary

Introduction: The epidemiological transition is one of the factors related to the increase in the prevalence of chronic noncommunicable diseases (CNCD), such as cardiovascular diseases, diabetes and cancer. Among the risks of risk to the development of CNCD are obesity, smoking, alcoholism, sedentary lifestyle and inadequate eating habits, with the last two levels having a high impact on gender and disease progression. Objectives: To promote healthy eating habits and to combat physical inactivity through nutritional monitoring and regular physical exercise, using a competition to stimulate adherence of the institution's employees. Methods: The present project is in agreement with the longitudinal study with the work of evaluation (anthropometric, body composition, laboratory and food consumption), in the eats of the times (at the beginning and end of the four-month intervention period). According to nutritional monitoring and individual guidance on regular physical exercise practice over a period of 12 weeks. Weight reduction, body fat reduction, changes in working methods and eating habits, and the relationship to routine physical activity after the intervention period, and are retested after six months. Expected results: Reduction of sedentary lifestyle, weight loss and body fat, improvement of eating habits, quality of life without working environment and health condition of the participants.

Manipulative and Massage Therapy in the Lower Thoracic and Cervical Spine in Subjects With Fibromyalgia Syndrome

  • Status
    Active, not recruiting
  • Phase
    N/A
  • Condition
    Fibromyalgia
View Full Trial
INTERVENTION

Other: Manipulative and Massage Therapy, Other: Exercise Program

Eligibility
  • Ages:
  • Sexes: All
  • Accepts Healthy Volunteers:
Locations

Adelaida María Castro-Sánchez, Almeria, Spain

Brief Summary

Objective: Compare degree of improvement can reach patients diagnosed with fibromyalgia syndrome, by treatment with Manipulative and Massage Techniques versus an exercise program for lower thoracic and cervical spine. Study Design: A single-blind randomized controlled trial was conducted on patients with fibromyalgia syndrome (FMS). Setting: Clinical setting. Methods: Sixty-four subjects with FMS were randomly assigned to an experimental group receiving manipulative and massage therapy, or to a control group for exercise program.

Kinesio Taping and Inhibitory Treatment Techniques

  • Status
    Active, not recruiting
  • Phase
    N/A
  • Condition
    Fibromyalgia
View Full Trial
INTERVENTION

Other: Kinesio Taping and Inhibitory Treatment Techniques, Other: Exercise and Electrical Stimulation Therapy

Eligibility
  • Ages:
  • Sexes: All
  • Accepts Healthy Volunteers:
Locations

Adelaida María Castro-Sánchez, Almería, Spain

Brief Summary

Objective: Compare the benefits of Kinesio Taping and Inhibitory Treatment Techniques for Cervical, Thoracic and Lumbar Spine in Patients with Fibromyalgia Syndrome (FMS). Study Design: A single-blind randomized controlled trial was conducted on patients with FMS. Setting: Clinical setting. Methods: Sixty-four subjects with FMS were randomly assigned to an experimental group receiving kinesio taping and inhibitory treatment techniques, or to a control group for exercises and electrical stimulation therapy.

Promoting Safe Use of Pediatric Liquid Medications

  • Status
    Active, not recruiting
  • Phase
    N/A
  • Condition
    Medication Errors
View Full Trial
INTERVENTION

Other: New Labeling/Dosing Strategy

Eligibility
  • Ages:
  • Sexes: All
  • Accepts Healthy Volunteers:
Locations

Stanford University School of Medicine, Stanford, California, United States

Brief Summary

Variable and poor-quality drug labeling has been cited as a leading cause of medication errors and adverse drug events, especially in the context of low health literacy. This is a particularly important issue in pediatrics as more than half of US children are exposed to one or more outpatient medications in a given week, and studies suggest that over half of caregivers make errors when dosing liquid medications for children. Our study objective is to identify evidence-based strategies for labeling and dosing prescription and over-the-counter pediatric liquid medications in order to promote safe, appropriate use, as well as to inform state and federal policy standards. We hypothesize that a health literacy-informed labeling and dosing strategy will result in improved parent ability to administer medications prescribed to their young children.

Severe Asthma Research Program (SARP)- San Francisco Clinical Site

  • Status
    Active, not recruiting
  • Phase
    N/A
  • Condition
    Asthma
View Full Trial
INTERVENTION

Not provided

Eligibility
  • Ages:
  • Sexes: All
  • Accepts Healthy Volunteers:
Locations

University of California, San Francisco, San Francisco, California, United States

Brief Summary

The mission of SARP is to improve the understanding of severe asthma through integrated study of its clinical and biological features and to evaluate their changes over time. The ultimate goal of these efforts is to promote better treatments for severe asthma.

Assessment of Severe Extremity Wound Bioburden at the Time of Definitive Wound Closure or Coverage

  • Status
    Active, not recruiting
  • Phase
    N/A
  • Condition
    Open Fracture
View Full Trial
INTERVENTION

Not provided

Eligibility
  • Ages:
  • Sexes: All
  • Accepts Healthy Volunteers:
Locations

Naval Medical Center San Diego, San Diego, California, United States

Brief Summary

The purpose of this study is to characterize the bacteria in the wound "bioburden" at the time of definitive wound coverage/closure of severe tibia fractures in both the military and civilian populations.