- Solid Tumors
- Pipeline Molecules
- Alliance Partners
Our mission is to provide healthcare professionals with unbiased clinical research information, easily.
Currently, you can access the following clinical trials being conducted worldwide:
Clinicaltrials.gov identifier NCT02970188
Recruitment Status Active, not recruiting
First Posted November 21, 2016
Last update posted June 14, 2019
The purpose of this study is to assess the safety and efficacy of time-restricted feeding (eating within an 8-hour window) for improving physiological function (vascular, motor, cognitive and metabolic function) in healthy middle-aged and older adults.
Overall, the proposed research project has the long-term potential to influence clinical practice by establishing novel therapies for treating multiple domains of age-associated physiological dysfunction and thereby reducing the risk of clinical disease and disability.
|Experimental: Time Restricted Feeding
Subjects will be instructed to eat with an 8 hour feeding window, starting between 10:30-11:30 AM and stopping between 5:30-6:30 PM.
Behavioral: Time Restricted Feeding
consuming all daily calories within an 8 hour feeding window
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, , Learn About Clinical Studies.-->
- Ability to provide informed consent
- Baseline brachial flow-mediated dilation (FMD) 1 year.
- Ages 3 vigorous bouts/week)
- Not weight stable in the prior 3 months (>2 kg weight change).
- Body mass index (BMI) >40 kg/m^2 (rationale: vascular function measurements can be
inaccurate in severely obese subjects)
- Current smoking
- Diagnosis of a chronic clinical disease (e.g., coronary artery/peripheral
artery/cerebrovascular diseases, diabetes, chronic kidney disease requiring dialysis,
neurological disorders or diseases that may affect motor/cognitive functions [multiple
sclerosis, Parkinson's disease, polio, Alzheimer's disease, dementia or other brain
diseases of aging]), except hypertension and hyperlipidemia.
- Having unstable angina, acute myocardial infarction, coronary angioplasty, or aorto-
coronary bypass surgery as defined by the occurrence of an event, symptom, surgery, or
change in medication and/or dosage within 3 months prior to enrollment.
- Having thyroid disease that is not controlled by medications or <3 month's use of a particular medication and/or dosage (rationale: uncontrolled thyroid diseases are associated with alterations in vascular function). - Having past or present alcohol dependence or abuse, as defined by the American Psychiatry Association, Diagnostic and Statistical Manual of Mental Disorders
United States, Colorado
Integrative Physiology of Aging Laboratory
University of Colorado, Boulder
Colorado State University
Principal Investigator: Christopher R Martens, Ph.D. University of Colorado, Boulder