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Currently, you can access the following clinical trials being conducted worldwide:
Clinicaltrials.gov identifier NCT03919305
Recruitment Status Not yet recruiting
First Posted April 18, 2019
Last update posted April 18, 2019
This study was aimed to reveal the clinical features,natural history of the diseases and current therapeutic situations of cerebral venous thrombosis (CVT) in China mainland. Blood samples and cerebrospinal fluid samples will be collected after recruitment to reveal the pathological mechanisms of CVT and identify the biomarkers for CVT.
cerebral venous thrombosis (CVT) is caused by a clot in the cerebral vein, which resulted in an obstruction of the blood outflow. CVT mainly includes cerebral venous sinus thrombosis, deep cerebral vein thrombosis and cortical vein thrombosis. However, the epidemiological features of CVT in China mainland remained obscure. This study was aimed to establish a multicenter cohort recruiting patients with CVT across 31 provinces and municipalities in China mainland. Clinical features,natural history of the diseases and current therapeutic situations will be analyzed to reveal the epidemiological features of CVT. Blood samples and cerebrospinal fluid samples will be collected after recruitment to reveal the pathological mechanisms of CVT and identify the biomarkers for CVT. Patients will be followed-up at 1, 3, 6, 12 months from baseline to evaluate the clinical prognosis and therapeutic outcomes.
DNA detection will be conducted in a ramdom selection of 300 blood samples.
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• Cerebral venous sinus thrombosis, deep cerebral vein thrombosis and cortical vein
thrombosis diagnosed by digital subtraction angiography (DSA), magnetic resonance
venography (MRV), computed tomography venography (CTV) or high-resolution magnetic
resonance imaging (HR-MRI).
• None of the patient, trustee or immediate family members signed the informed consent.
Contact: Min Li, MD, PhD +86-18701519698 email@example.com
Capital Medical University
Beijing Municipal Science & Technology Commission
Principal Investigator: Xunming Ji, MD, PhD Xuanwu Hospital, Beijing