- Solid Tumors
- Pipeline Molecules
- Alliance Partners
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Currently, you can access the following clinical trials being conducted worldwide:
Clinicaltrials.gov identifier NCT03924128
Recruitment Status Available
First Posted April 23, 2019
Last update posted March 27, 2020
PhotoBioModulation (PBM) is a mature science with therapeutic efficacy in humans and animals, and with excellent results in different medical specialties without side effects. However there are gaps that prevent adoption on a large scale. Recent research developed by our group and partners allowed us to understand the mechanisms of action of PBM, from Molecular Physics through Biochemistry and with consequent clinical validation, with precise, replicable and personalized therapeutic results. These findings have led to treatments for many kinds of pains with industrial predictability and accuracy, phenotypic adequacy technologies that are encapsulated, prescribed, and applied. Photobiomodulation applications cover treatments for pain, inflammation, tissue regeneration, healing, immune system activation, all of which are essential characteristics for osteoarthritis therapy. Our idea is to formulate great challenges of Photobiomodulation as a solution to osteoarthritis as follows: 1) Make PBM-based therapies as predictable as drug-based therapies; this is possible with precise dose calculation performed by our team; 2) Map the biochemical and molecular effects of PBM, including those related to gene expression; 3) Unify PBM theory by synthesizing and giving meaning to the millions of PBM data associated with osteoarthritis and correlating with clinical study to be performed under this thematic project. Overcoming these challenges, PBM will become a complementary (or supplementary) alternative to medications, physiotherapy and surgical procedures for the treatment of osteoarthritis.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, , Learn About Clinical Studies.-->
- Male and female subjects age ≥ 20 years old
- Diagnosed with Osteoarthritis stages III and IV according to the American College of
- Functional impairment for more than 3 months, able to wander with or without canes.
- History of cancer
- Unstable cardiovascular disease
- uncontrolled hypertension
- morbid obesity, that is, BMI ≥ 40
- terminal illness
- cerebrovascular disease
- heart pacemaker
- superior or inferior limb fractures.
Contact: Marucia Chacur, PhD +551130918452 firstname.lastname@example.org
Contact: Hazel Abel Ashmawi, M.D. email@example.com
University of Sao Paulo
University of Sao Paulo
Principal Investigator: Nathalia Lopes Ferreira, Undergraduate University of Sao Paulo