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Currently, you can access the following clinical trials being conducted worldwide:
Clinicaltrials.gov identifier NCT03924583
Recruitment Status Recruiting
First Posted April 23, 2019
Last update posted April 23, 2019
Catheter-related thrombosis (CRT) has been found as the major complication of the established central venous catheter in intensive care unit (ICU) patients. Its reported incidence varies from 5 to 66 %. Although most cases are asymptomatic, in up to 10 - 15 % of the patients pulmonary embolism occurs. In addition, CRT is associated with the risk of infection, post-thrombotic syndrome and with general disruption of the management of the underlying disease. The most accessible diagnostic method for CRT recognition is duplex ultrasonography. However, screening of CRT by duplex ultrasonography is not common approach in ICUs. Normally, duplex ultrasonography is performed by physicians. In this setting, implementation of the screening in ICU would be time consuming and practically unrealizable. Delegating this competence to ICU nurses can increase availability of this screening method. Therefore, as a first step, investigators decided to perform a validation clinical study to verify the diagnostic accuracy of duplex ultrasonography of the venous system for CRT screening performed by a general nurse.
Approximately 150 patients with central venous catheter will be enrolled in this study. Investigators: 1. General nurses - trained and able to perform duplex ultrasonography examination of venous circulation 2. Doctors - experienced specialists in intensive care or urgent medicine Every patient with central venous catheter enrolled in clinical study is examined with duplex ultrasonography within 24 hours by both investigators, doctor and nurse. Each examination includes ultrasonography of a whole vena cava venous system with central venous catheter, bilaterally. Results of both examinations are blinded until the end of study, with one exception. In case of positive result - catheter related thrombosis is present, investigator ( nurse )informs patients attending physician. Results of investigations are recorded in Investigation Form with some other routine medical data. Timetable: 18.3.2019 - 30.6.2020: Enrolling, collection of data 1.7.2020 - 30.9.2020: Finalization od database, statistic analysis 1.10.2020 - 31.1.2021: Preparation of publications 1.2. 2021 - 31.12.2021: Result presentation
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, , Learn About Clinical Studies.-->
- central venous catheter more than 48 hours in situ
- consent of a patient
- technical difficulties of ultrasound machine
- unfavorable local findings - inflammation of skin, excoriation etc.
Contact: Barbora Pakostová, M.D. +420477112202 firstname.lastname@example.org
Clinic of anaesthesiology, resuscitaion and perioperative care, Masaryk Hospital,
Ústí Nad Labem
Masaryk Hospital Krajská zdravotní a.s.
Principal Investigator: Barbora Pakostová, M.D. Krajská zdravotní a.s., Masaryk Hospital