April 25, 2019
April 26, 2019
The study investigates the effects of consumption of yoghurt enriched with vitamins B compared to plain yoghurt, on body weight management and glycemic control of overweight/obese T2DM patients. It also investigates the effect of plain yoghurt consumption on gut hormones response of T2DM patients.
In a large number of epidemiological studies, low-fat dairy consumption has been associated with lower risk of T2DM. However, the number of randomized clinical trials which examine the impact of yoghurt consumption on glycemic control and body weight management of T2DM patients is small and include yoghurts fortified with vitamin D or probiotics. According to our knowledge, fortification of yoghurt with other classes of vitamins beyond vitamin D has not been examined. Vitamins of B-complex hold key-role in energy metabolism. In the state of diabetes mellitus, the requirements for this vitamin class may be higher because of their water solubility and increased excretion. Two groups of patients participated in the study. One group received yoghurt enriched with vitamins B and one group received isocaloric plain yoghurt. In addition, in order to investigate the effect of plain yoghurt on gut hormones, responses to a mixed meal tolerance test were evaluated in the beggining and the end of the dietary intervention.
|Active Comparator: Plain yoghurt
2x200g plain yoghurt/day for 12 weeks
Other: Plain yoghurt
cups of 200 g yoghurt
|Experimental: Vitamin B yoghurt
2x200g yoghurt enriched with vitamins B for 12 weeks
Other: Vitamin B yoghurt
cups of 200 g yoghurt
- BMI 27-36
- HbA1C 2 drinks per day)
- Intake of supplements
- Receiving insulin
National and Kapodistrian University of Athens
Principal Investigator: Amalia Yanni Harokopio University
Study Chair: Nikolaos Tentolouris National and Kapodistrian University of Athens
Study Director: Vaios Karathanos Harokopio University
El Khoury D, Brown P, Smith G, Berengut S, Panahi S, Kubant R, Anderson GH. Increasing the protein to carbohydrate ratio in yogurts consumed as a snack reduces post-consumption glycemia independent of insulin. Clin Nutr. 2014 Feb;33(1):29-38. doi: 10.1016/j.clnu.2013.03.010. Epub 2013 Mar 27.