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Currently, you can access the following clinical trials being conducted worldwide:
Clinicaltrials.gov identifier NCT03927118
Recruitment Status Completed
First Posted April 25, 2019
Last update posted May 13, 2019
This study evaluates the effect of dexamethasone implant which is an intraocular corticosteroid on the optic nerve fibers. Retinal nerve fiber thicknesses and optic nerve head pitting rates were measured before and 6 months after the injection.
Diabetic macular edema is the most frequent ocular complication of diabetes resulting in irreversible loss of vision if untreated. Dexamethasone implant implant is used to treat macular edema due to diabetes. It stay in the vitreous for 6 months after intravitreal administration. Dexamethasone implant can lead to retinal nerve fiber layer and optic nerve damage by both increasing intraocular pressure and its direct effect on neural tissue during the effective 6-month period.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, , Learn About Clinical Studies.-->
Patients who underwent first time intravitreal injection
Previously received any surgery
Proliferative diabetic retinopathy
Glaucoma or glaucoma suspicion
Optic disc fatigue
Optic disc edema
Uveitis and media opacity
Blurred of image clarity
Zonguldak Bülent Ecevit Üniversitesi.
Bulent Ecevit University
Study Director: Atilla Alpay, Ass. Prf. Zonguldak Bulent Ecevit University
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