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Our mission is to provide healthcare professionals with unbiased clinical research information, easily.
Currently, you can access the following clinical trials being conducted worldwide:
Clinicaltrials.gov identifier NCT03932032
Recruitment Status Active, not recruiting
First Posted April 30, 2019
Last update posted April 10, 2020
This two-site study is a test of Attention Bias Modification Treatment (ABMT) among 260 youths ages 10 to 14 years with social anxiety disorder. One-half of participants will receive 8 sessions of computer administered ABMT and the other half of participants will receive 8 sessions of computer administered Neutral Control Task (NCT). The investigators hypothesize that a biomarker of attention to social threat measured using electroencephalography (EEG) and ratings of social anxiety severity will be lower in participants who receive ABMT compared to participants who receive NCT.
|Experimental: Attention Bias Modification Treatment
Attention Bias Modification Treatment is a computer-based attention training program.
Behavioral: Attention Bias Modification Treatment
At each of eight sessions, participants complete 160 computer administered trials wherein a pair of threatening stimuli and neutral stimuli is presented simultaneously and then followed immediately by a probe. The probe always replaces the neutral stimulus and never replaces the threatening stimulus. The intervention is based on the idea that attention can be shaped via repetitive computer based training methods, and training attention toward neutral stimuli will lead to a reduction in social anxiety.
|Sham Comparator: Neutral Control Task
Neutral Control Task uses the same computer-based format as Attention Bias Modification Treatment, but includes only neutral stimuli and does not train attention.
Behavioral: Neutral Control Task
At each of eight sessions, participants complete 160 computer administered trials wherein a pair of neutral stimuli is presented simultaneously and then followed immediately by a probe. NCT matches ABMT on duration, format, and number of trials, but does not engage attention to social threat and does not train attention.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, , Learn About Clinical Studies.-->
- Be between ages 10 and 14 years
- meet DSM5 criteria for a diagnosis of Social Anxiety Disorder
- presence of any coexisting psychiatric diagnoses must be of lesser severity than
Social Anxiety Disorder
- have no current psychotropic medication other than a stable dose of stimulant or
non-stimulant medication for coexisting ADHD
- meet DSM5 criteria for Autism Spectrum Disorder, Intellectual Disability, Bipolar
Disorder, Tourette's Disorder, Psychotic Disorders, or Substance Use Disorders
- show high likelihood of hurting self or others
- be a victim of undisclosed abuse requiring investigation/ supervision by the
Department of Social Services
- have an uncorrected vision or physical disability that interferes with the ability to
click a mouse button rapidly and repeatedly
- have a history of neurological illness, including seizures/epilepsy, or head injury
with loss of consciousness > 5 minutes
United States, Connecticut
Yale Child Study Center Program for Anxiety and Mood Disorders
United States, Florida
Florida International University Center for Children and Families
Florida International University
Principal Investigator: Jeremy W Pettit, PhD Florida International University
Principal Investigator: Wendy K Silverman, PhD Yale University