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Currently, you can access the following clinical trials being conducted worldwide:
Clinicaltrials.gov identifier NCT03932214
Recruitment Status Not yet recruiting
First Posted April 30, 2019
Last update posted December 17, 2019
Peripheral venous catheterization is a fundamental part of the management of critically-ill patients, especially for administration of intravenous emergency treatments. In general, it is preferred to central catheterization whenever possible, since it is less invasive, achievable immediately by the nurse, and responsible for fewer complications. Venous access difficulties are frequent in critically-ill patients. Among tools proposed to improve the practice of peripheral catheterization, ultrasound and infrared illumination are the most studied, the latter being simpler. Infrared illumination has never been evaluated in intensive care. However, the delay or failure of peripheral catheterization is highly detrimental in the context of resuscitation as it may delay or impede appropriate management of vital emergencies. Our study will focus on the peripheral venous catheterization of the upper limbs, as these are the reference site for this technique The objective is to evaluate the interest of infrared illumination (AccuVein AV500®) for the primary success (first puncture) of peripheral venous catheterization of the upper limbs in patients with resuscitation at risk of catheterization venous difficult. It is a comparative, superiority, prospective, multicenter, randomized, controlled, open-label, phase III trial. Subjects will be divided into two groups with a 1: 1 ratio. Nurses at participating centers will be trained for the use of the device prior to the start of the study; the use of the device is singularly easy and intuitive.
|Experimental: Infrared illumination group
The nurse uses the Accuvein® device to identify the veins before puncture.
The nurse uses the Accuvein® device to identify the veins before puncture and then proceeds as usual, under illumination of the device.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, , Learn About Clinical Studies.-->
- Age ≥ 18 years; Hospitalization in intensive care;
- Need for a peripheral venous catheter;
- Risk of difficult peripheral venous catheterization. In practice, this risk will be
considered present if it is impossible to palpate and / or visualize the upper end of
the target vein and / or if the estimated vein diameter is smaller than 2mm. This
definition is derived from the A-DIVA score (Loon FAJ van et al3).
- Affiliation to the social security
- Patient who has already been enrolled in the ICARE study during the current
- Refusal of patient's participation
Contact: Fabien BOUSSELY, senior officer 01 49 81 42 50 ext 33 email@example.com
Contact: Akim SOUAG (0)1 44 84 17 15 ext 33 firstname.lastname@example.org
Assistance Publique - Hôpitaux de Paris
Principal Investigator: Fabien BOUSSELY, senior officer Assistance publique des hopitaux de Paris
Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R; Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013 Feb;41(2):580-637. doi: 10.1097/CCM.0b013e31827e83af.
van Loon FH, Puijn LA, Houterman S, Bouwman AR. Development of the A-DIVA Scale: A Clinical Predictive Scale to Identify Difficult Intravenous Access in Adult Patients Based on Clinical Observations. Medicine (Baltimore). 2016 Apr;95(16):e3428. doi: 10.1097/MD.0000000000003428.