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Clinical trial information and results are updated daily from ClinicalTrials.gov. The latest data update was conducted on 06/15/2021.

Tendon Transfer for Irreversible Radial Nerve Palsy, Does it Help?Retrospective Cohort From Level-1 Trauma Center.

Clinicaltrials.gov identifier NCT03936868

Recruitment Status Completed

First Posted May 3, 2019

Last update posted May 3, 2019

Study Description

Brief summary:

Radial nerve palsy is associated with serious disability jeopardizing the grasp and power grip accountable to the loss of thumb and fingers extension and loss of active wrist extension respectively. There are three aims in the treatment of radial nerve palsy which comprise the restoration of thumb extension and abduction, finger extension and restoration of wrist extension. In this study we measured the functional outcome after tendon transfer for radial nerve palsy aimed to restore the wrist extension, finger extension and thumb extension/abduction. Investigators' objective was to assess the functional outcome after tendon transfer surgery for radial nerve palsy.

  • Condition or Disease:Radial Palsy
  • Intervention/Treatment: Procedure: Tendon transfer
  • Phase: N/A
Detailed Description

Radial nerve palsy is associated with serious disability jeopardizing the grasp and power grip accountable to the loss of thumb and fingers extension and loss of active wrist extension respectively. There are three aims in the treatment of radial nerve palsy which comprise the restoration of thumb extension and abduction, finger extension and restoration of wrist extension. In this study we measured the functional outcome after tendon transfer for radial nerve palsy aimed to restore the wrist extension, finger extension and thumb extension/abduction. Investigators' objective was to assess the functional outcome after tendon transfer surgery for radial nerve palsy. So investigators conducted a retrospective study at Aga Khan University Hospital Karachi comprising records of patients operated for irreversible high radial nerve palsy. Investigators concluded that tendon transfer surgery for radial nerve palsy provides excellent results to restore the lost function and therefore must be considered for patients with no signs of recovery after the nerve repair.

Study Design
  • Study Type: Observational
  • Actual Enrollment: 49 participants
  • Observational Model: Cohort
  • Time Perspective: Prospective
  • Official Title: Tendon Transfer Surgery for Irreversible Radial Nerve Palsy, Does it Help When Expert is Available? Retrospective Cohort From Level-1 Trauma Center in a Metropolitan City.
  • Actual Study Start Date: January 2004
  • Actual Primary Completion Date: December 2014
  • Actual Study Completion Date: December 2014
Groups and Cohorts
Groups/Cohorts Intervention/treatment
: Tendon transfer for irreversible radial nerve palsy patient
Tendon transfer for irreversible radial nerve palsy patient who had irreversible damage to radial nerve due to trauma with different mechanism especially gun shot injury
Procedure: Tendon transfer
flexor carpi radialis transfer in most of patients and boye-transfer in very few
Outcome Measures
  • Primary Outcome Measures: 1. Functional outcome - Range of Motion [ Time Frame: 6 months ]
    Range of Motion at hand and wrist joints, fingers extension, wrist extension
Eligibility Criteria
  • Ages Eligible for Study: (Child, Adult, Older Adult)
  • Sexes Eligible for Study: All
  • Accepts Healthy Volunteers: Yes
  • Sampling Method: Non-Probability Sample
  • Study Population: participants with presenting due to late consequence of trauma affecting their hand and wrist function due to irreversible damage to radial nerve
Criteria

Inclusion Criteria:

- All participants including paediatric and adult age group with irreversible radial
nerve palsy and patients with radial nerve palsy with time interval of more than 9
months were included.

Exclusion Criteria:

- All participants who underwent radial nerve repair or nerve grafting with or without
internal splinting, patients with vascular injuries, muscular dystrophies, CVA
(Cerebero-Vascular Accident), Dementia and those with limited followup of less than 3
months were excluded.

Contacts and Locations
Contacts
Locations
Sponsors and Collaborators

Aga Khan University

More Information
  • Responsible Party: Aga Khan University
  • ClinicalTrials.gov Identifier: NCT03936868 History of Changes
  • Other Study ID Numbers: 2019-0845-3203
  • First Posted: May 3, 2019 Key Record Dates
  • Last Update Posted: May 3, 2019
  • Last Verified: May 2019
  • Individual Participant
    Data (IPD) Sharing
    Statement:
  • Plan to Share IPD: No
  • Plan Description: Not having permission from institute.
  • Additional relevant MeSH terms: Radial Neuropathy