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Currently, you can access the following clinical trials being conducted worldwide:
Clinicaltrials.gov identifier NCT03942315
Recruitment Status Completed
First Posted May 8, 2019
Last update posted May 8, 2019
Liver transplantation (LT) has been proposed as a curative treatment in hereditary hemorrhagic telangiectasia (HHT) with severe hepatic involvement. The investigating team provides a long-term evaluation of graft status after LT for HHT with a focus on the risk of recurrence. The present study included all patients prospectively followed up after LT for HHT in the Lyon Liver Transplant Unit from 1993 to 2010 with a survival of more than 1 year.
|: Liver transplant in Hereditary Hemorrhagic Telangiectasia
Hereditary Hemorrhagic Telangiectasia (HHT) patients who underwent a liver transplant in Lyon between 1993 and 2010, and who survived more than 1 year after transplantation.
Other: Data collection from standard follow-up after liver transplant
All patients underwent regular follow-up every 6 to 12 months after the first year post-liver transplant (LT). Complete laboratory investigations were performed at each visit. Doppler ultrasonography was performed every 1 to 3 years after LT. Computed tomography (CT) scan and/ or magnetic resonance imaging (MRI) was performed at 1, 5, 10, 15, and 20 years after LT, or when clinically indicated. All available radiological material was reviewed. Cardiac evaluation was performed regularly in patients who received transplant for cardiac failure.
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- Hereditary Hemorrhagic Telangiectasia (HHT) patient who underwent liver transplant for
- Patient who died in the year following transplantation
Hospices Civils de Lyon
Principal Investigator: Jérôme DUMORTIER, MD Hospices Civils de Lyon (Hôpital Edouard Herriot )